Monday, September 17, 2012

orexin

orexin, the appetite hormone?

http://blogs.scientificamerican.com/scicurious-brain/2012/09/17/orexin-and-binge-eating-rats/

http://en.wikipedia.org/wiki/Orexin

4 comments :

  1. what i'd like to know is, do other molecules imitate it, in the body! does it have competitors -- that kind of thing! interesting stuff....

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  2. does it have competitors

    yes ... Leptin

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  3. do other molecules imitate it...

    yes... it is a peptide, so some protein will digest into orexin and orexin like... perhaps wheat (glutin group)...nuts...

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  4. sorry -- i missed that, reading too fast the first time. since, as Kindke says, leptin secretion is encouraged by glucose going the lipogenesis route in adipocytes, i would expect to be more hungry than i am, having little to compete with the orexin. however, my VLC diet seems to suppress appetite quite a bit, and the ghrelin which SHOULD "activate" the orexin is in lower supply and my rock-steady blood sugar inhibits it too. (thinking out loud here....)

    VERY interesting indeed, Fred -- thanks!

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